Abstract
Abstract o 1. Antidiuretic responses of Dipdomys spectabilis and Rattus norvegicus were compared before and after 4 days of water deprivation. 2. Nicotine caused a delay in the onset of diuresis and an increase in urine osmolality and chloride concentration in both species receiving water ad lib . 3. Nicotine induced antidiuresis in the water deprived D. spectabilis , but not in the water deprived R. norvegicus . 4. Azacyclonol produced antidiuresis with associated increases in urine osmolality and chloride concentration in both species before and after water deprivation.
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