Effect of Vitamin D Supplementation on 25(OH)D Status in Elite Athletes With Spinal Cord Injury.

Abstract

Recent studies suggest that a substantial proportion of athletes with spinal cord injury have insufficient 25(OH) vitamin D (25(OH)D) status, which may be associated with decreased muscle strength. This study consisted of two parts: (a)to examine the effects of a 12- to 16-week vitamin D3 supplementation protocol on 25(OH)D concentration and (b)to determine whether subsequent 25(OH)D status impacts muscle performance in elite athletes with spinal cord injury. Thirty-four members (age: 33 ± 15 years, weight: 69.6 ± 28.2kg, and height: 170.2 ± 25.4cm) of the U.S. and Canadian Paralympic program participated in the study. 25(OH)D concentrations and performance measures (handgrip strength and 20-m wheelchair sprint) were assessed pre- and postsupplementation. Participants were assigned a vitamin D3 supplementation protocol based on initial 25(OH)D concentrations. Participants with deficient 25(OH)D status (<50nmol/L) received 50,000IU/week for 8 weeks, and participants with insufficient status (50-75nmol/L) received 35,000IU/week for 4 weeks, after which both received a maintenance dose of 15,000IU/week. Participants with sufficient status (>75nmol/L) received the maintenance dose of 15,000IU/week. 25(OH)D concentrations increased significantly (p < .001; 66.3 ± 24.3nmol/L and 111.3 ± 30.8nmol/L pre- and postsupplementation, respectively). About 26% of athletes had sufficient 25(OH)D concentrations presupplementation, and 91% had sufficient concentrations postsupplementation. About 62% of participants improved handgrip strength postsupplementation with no change in 20-m wheelchair sprint performance. The supplementation protocol was effective for achieving sufficient vitamin D concentrations in elite athletes with spinal cord injury.