Abstract

To study the effect of fetal rat spinal cord tissue transplants with different gestational days on the repair of transected spinal cord in adult rats, fetal rat spinal cord tissue obtained on gestational day 12, 13 and 14 was implanted to the cavity in the transected spinal cord in adult rats. The routine histologic examinations were performed postoperatively. The results revealed a total graft survival rate of 82.5 % . The transplants could have a better growth and differentiation, and integrate with the recipient spinal cord tissues at the injured sites. The transplant in gestation day 13 may be the best donor tissue because it had the greatest potential for promoting the repair of the transected host spinal cord. Key words: Spinal-cord injuries; Embryo; Spinal-cord; Transplantation

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