Abstract
The effect of some drugs on reflex vasodilatation in the hand was studied. Bretylium tosylate and phenoxybenzamine abolished the reflex vasodilator response in the hand caused by cradle heating of the chest. Alpha methyl dopa, nethalide, and atropine had no effect on this response. It is suggested that the tonic constriction of hand vessels maintained by sympathetic fibers and alpha adrenergic constrictor receptors is temporarily interrupted by 40 sec cradle heating of the chest and that this produces the observed increase in hand blood flow. The reflex increase in hand blood flow with short cradle heating of the chest appears to utilize a common efferent pathway with the vasodilator response produced in the hand by prolonged heating of the legs. On the afferent side, however, these reflexes use different mechanisms. afferent and efferent pathways; alpha methyl dopa; nethalide; atropine; receptors on hand vessels; bretylium tosylate; phenoxybenzamine Submitted on February 24, 1964
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
