Abstract
Colonization of silicone-based soft lining materials by pathogenic yeast-type fungi is a common problem associated with the use of dentures. In this study, silver sodium hydrogen zirconium phosphate (SSHZP) was introduced into polydimethylsiloxane-based material as an antimicrobial filler at concentrations of 0.25, 0.5, 1, 2, 4, 6, 8, 10, 12, and 14% (w/w). The in vitro antimicrobial efficacy was investigated. Candida albicans was used as a characteristic representative of pathogenic oral microflora. Staphylococcus aureus and Escherichia coli were used as the typical Gram-positive and Gram-negative bacterial strains, respectively. The effect of filler addition on the Shore A hardness, tensile strength, tensile bond strength, sorption, and solubility was investigated. An increase in the filler concentration resulted in an increase in hardness, sorption, and solubility, and for the highest concentration, a decrease in bond strength. The favorable combination of antimicrobial efficacy with other properties was achieved at filler concentrations ranging from 2% to 10%. These composites exhibited mechanical properties similar to the material without the antimicrobial filler and enhanced in vitro antimicrobial efficiency.
Highlights
Soft denture lining materials are used in prosthetic dentistry to help in more even distribution of biting loads transmitted by dentures to soft tissues during chewing [1]
We report the use of silver sodium hydrogen zirconium phosphate (SSHZP)
The problems related with filler aggregation in the polymeric composites have been well-documented and reported for numerous laboratory-scale investigations [39], for the poly(methyl methacrylate) (PMMA) denture base material modified with SSHZP [40]
Summary
Soft denture lining materials are used in prosthetic dentistry to help in more even distribution of biting loads transmitted by dentures to soft tissues during chewing [1]. Soft lining materials possess the ability to absorb part of functional stress [2]. This may relieve the mucosa from a high, local mechanical stress, which supports prosthetic treatment [3]. Soft linings can be categorized as tissue conditioners, intended for short-term use, and long-term soft linings, which may work in the oral cavity for more than four weeks, but they are usually used for many months or even several years [3,8]. Most of the currently available long-term soft linings are silicone rubbers, which are room temperature vulcanized (RTV) or heat temperature vulcanized (HTV)
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