Abstract
The effect of safflower oil emulsion given as a supplement to the usual diet was studied in 24 young men, weekly samples of blood being taken and analyzed for total cholesterol. After an initial period of five weeks, the subjects were divided into two groups who received either safflower oil emulsion or a placebo for seven weeks. At the end of that time the two groups were reversed, so that those who had received the placebo now received emulsion and vice versa. Neither the subjects nor the supervising physicians knew which preparation a given subject was receiving at a given time. The emulsion, containing 65% safflower oil, was given in 15-cc. doses five times daily to a total of 75 cc. each day. Used as a supplement to the usual diet under these conditions, it had no demonstrable depressant effect on the total serum cholesterol levels.
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