Abstract

Background: Nebulization Salbutamol has important role in the treatment of Acute wheeze despite of reported electrolyte imbalance so this study was conducted to know the changes in serum potassium level post Nebulization. Methods: A Cross-sectional observational study was conducted among 67 children aged 12-60 months presenting with acute wheeze at tertiary health care center. Baseline clinical parameters heart rate, respiratory rate, SpO2 along with serum potassium level was compared before and post repeated Salbutamol Nebulization. Results: The mean age of the study population was 35.95 months. The mean number of repeated Salbutamol Nebulization was 4.9 over mean time of 151 mins. There was significant increase in heart rate, decrease in respiratory rate and SpO2 post Salbutamol Nebulization. The Mean ±SD serum potassium concentration before and after Post Nebulization was 4.44±0.85 mEq/L and 4.01±0.97 respectively and it was statistically significant (P<0.05, paired t-test). A fall in serum potassium was seen in 40 patients (59.70%). Conclusion: Nebulization Salbutamol causes changes in serum potassium level so it should be monitored. Keywords: Acute wheeze, Heart rate, Nebulization Salbutamol, Respiratory rate, SpO2, Serum potassium.

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