Abstract
Glucose-6-phosphate dehydrogenase activity in skeletal muscles of the lamprey (Lampetra fluviatilis) decreased during prespawning starvation (September-May). The observed changes were particularly pronounced in January. Insulin, insulin-like growth factor 1, and relaxin produce an in vitro stimulatory effect on the enzyme. Insulin was most potent in this respect. Inactivation of the enzyme was accompanied by a decrease in its sensitivity to the stimulatory effect of insulin and insulin-like growth factor 1.
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