Abstract
Effect of Modified Solvent Casting/Particulate Leaching (SCPL) Technique on the Properties of Bioactive Glass Reinforced Polyurethane Scaffold for Biomedical Applications
Highlights
Nowadays, current advances are being made with the developments of tissueengineered products
Bioactive composite scaffold containing PU and 45S5 bioactive glass was fabricated by conventional solvent casting/particulate leaching (SCPL) method and enhanced SCPL method
The total porosity of scaffolds fabricated by enhanced SCPL method is ranging approximately from 88% to 90%, whereas conventional SCPL method is approximately 81%
Summary
Current advances are being made with the developments of tissueengineered products. Scaffold-based tissue engineering consists of an artificial extracellular matrix (ECM) and three-dimensional (3D) scaffolds containing living cells and regulating biomolecules.[1] The scaffold mimics the central component that imitate ECM, whereas the cells and growth factors will interact with ECM to regenerate targeted tissues.[2] Mechanical properties of scaffold should match and bond to host bone without the scar tissue formation, besides providing a sufficient support for new bone formation. A porous and interconnected scaffold structure are important to ensure the waste products can be diffused out. The products of scaffold degradation should be able to exit the body without any reaction with other organs and the surrounding tissues.[1]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
