Abstract
To determine whether exposure to magnetic fields might have chronopharmacological effects on bone growth in rats, 150-g male animals were exposed to a 60-Hz magnetic field (average field strength, 10.2 Gauss) either during the day or during the night for 30 days. Serial tetracycline studies revealed a trend toward impaired periosteal growth/mineralization rates with both day and night exposures, but the data were not statistically different. Body weight gain, bone length, ratios of ash wt./dry fat-free wt., and metaphyseal trabecular volume were comparable In each of the two groups. This preliminary study suggested that a period of exposure longer than 30 days to a 60-Hz, 10.2 Gauss magnetic field might be required to produce significant skeletal effects.
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