Abstract
Effects of lactogenic hormone (LGH) alone and in combination with growth hormone (GH) and L-thyroxine (T4) upon lactation in the rat have been studied. All rats were nursed on day 14 of lactation with aid of 1 USP unit of oxytocin (OXT) under standardized conditions. One mg LGH alone did not show galactopoietic effects when injected daily from day 7–14. Under combined action of 1 mg LGH and 1 mg GH/day from 7–14, litter weight gain and amount of milk on day 14 have been significantly increased. Addition of 3.0 μg T4/100 g body weight/day from day 7–14 to LGH plus GH resulted in a more highly significant increase in milk yield in comparison to oxytocin alone than did treatment with LGH plus GH. The increase in mean milk yield of 84% over untreated controls by 4 hormones is the highest so far attained in laboratory.
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