Abstract

Background and Aims : Circulating microRNAs as a component of such epigenetic mechanism of posttranscriptional regulation of mRNA translation may serve as blood biomarkers of CVDs, moreover, the study of circulating miRNAs may help to identify potential therapeutic targets. We investigated changes in the serum level of 4 circulated microRNAs (miR-33a, miR-33b, miR-146a, and miR-146b) in patients with coronary artery disease and disorders of carbohydrate metabolism under the influence of up-titrated doses of two widely used statins (atorvastatin and rosuvastatin).

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