Abstract

As we previously reported and reconfirmed, SHRSP fed on the normal diet developed stroke, in average, at the age of 9 months in males. However, in the present study, SHRSP fed on the high protein (soybean protein in this study) diet maintained the normal range in both rCBF and chemical cerebrovascular reactivity in spite of the development of severe hypertension at the age of 8 month. These experimental results substantiated prophylactic effect of high protein diet on stroke from the view point of mechanism of stroke mentioned above in the introduction

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