Abstract
The effect of granulocyte-macrophage colony-stimulating factor (GM-CSF) on the functional state of the thymus in the treatment of gastrointestinal diseases in piglets was studied. The experiment was carried out on a large pig breeding farm in the Voronezh region. For the experiment, 3 groups of 20 sick piglets at the age of 5-7 days were formed in which gastrointestinal diseases of bacterial etiology were registered. The group 5 was the control, and the piglets of it did not receive treatment, the piglets of group 2 received the drug Quinocol, and the piglets of group 3 – Quinocol in combination with GM-CSF. Histological and immunohistochemical studies were carried out according to commonly accepted methods. As a result, a significant (p<0.01) decrease in CD-3 positive cells in the field of view by 12% in group 3 was shown, which was a consequence of cell migration from the thymus to peripheral organs. There were no significant differences in the number of PAX-5 cells.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Transactions of the educational establishment “Vitebsk the Order of “the Badge of Honor” State Academy of Veterinary Medicine
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
