Abstract

Background Appendicitis is the most common cause of surgery in people under 50. In America, it causes 250,000 cases per year and about 1 million days of hospitalization. Methods This cross-sectional study was performed on 20 patients under appendectomy with diagnosis of acute appendicitis. The statistical population was divided into two groups, proven appendicitis in pathology and rejection of appendicitis in pathology. Then, 10 patients were assigned into each group. Results A total of 20 patients were enrolled in this study, 9 of whom were female (45%) and 11 male (55%). The most common symptom was anorexia. However, there was no statistical difference between the two groups. The lowest level of serum ghrelin was 0.95 and the highest was 16.00 in the study group, which was the mean in people with appendicitis and nonappendicitis 6.24 ± 4.09 and 5.12 ± 4.85, respectively. These values were not significantly different between the two groups (T = 0.45, df = 18, p = 0.65). Conclusion This conclusion may be due to the small number of cases introduced into the study, which suggests that further investigation is warranted with a larger sample size.

Highlights

  • Appendicitis is a common disease in the United States causing 250,000 cases per year and approximately 1 million hospitalizations per day [1]

  • Different symptoms can complicate the diagnosis of acute appendicitis [1]

  • It was concluded that ghrelin was higher in patients with appendicitis than in nonappendicitis patients, this value was not statistically significant

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Summary

Introduction

Appendicitis is a common disease in the United States causing 250,000 cases per year and approximately 1 million hospitalizations per day [1]. There may be no abdominal findings at all when the inflamed appendix is inside the pelvis In this case, the diagnosis may be wrong unless rectal examination is done. The lowest level of serum ghrelin was 0.95 and the highest was 16.00 in the study group, which was the mean in people with appendicitis and nonappendicitis 6:24 ± 4:09 and 5:12 ± 4:85, respectively. These values were not significantly different between the two groups (T = 0:45, df = 18, p = 0:65). This conclusion may be due to the small number of cases introduced into the study, which suggests that further investigation is warranted with a larger sample size

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