Abstract
Effect of Ethanolic Olive Leaves Extract on the Renal Cortex of Adult Diabetic Male Albino Rats
Highlights
Diabetes mellitus (D) is one of the human disorders with the most severe metabolic consequences
20rats were treated with NA-STZ for induction of diabetes and all of them were diabetic; and they were categorized into two groups the first group served as the diabetic group and the second one was used in D+olive leaves extract (OLE) group
The renal ameliorative effect of ethanolic olive leaves extract on nicotinamide-streptozotocin-induced diabetic rats was performed
Summary
Diabetes mellitus (D) is one of the human disorders with the most severe metabolic consequences. Another study has shown rutin that oleuropein (up to 6%–9% of dry matter in the leaves) has been correlated with ameliorated glucose metabolism and is liable for the antihyperglycemic effect in diabetic rats (Barbaro et al, 2014). Hydroxytyrosol and oleuropein have been shown to be both potential α-glucosidase inhibitors for regulation of post-prandial high glycemia as the antidiabetic properties for various plant extracts by inhibiting carbohydrate-hydrolyzing enzymes (Hadrich et al, 2016). Wt.), levels of uric acid, creatinine and urea were significantly improved with normal liver function (Afify et al, 2018) It is evident from the previous literature that diabetes and renal dysfunctions are closely related. The present study was planned to assess the antidiabetic effect of olive leaf extract in the kidney cortex of diabetic adult male rats
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