Effect of diabetes mellitus and glycemic control on the prognosis of invasive bladder cancer

Abstract

A patient's prognosis for cancer treatment is thought to be affected by their presence of diabetes mellitus (DM). Epidemiological studies show that type 2 diabetes raises the risk of a wide range of cancers, including colorectal, breast, endometrial, and hepatocellular carcinoma. Findings for bladder cancer were hard to comprehend and thus no proof has been presented. Objectives: Invasive bladder cancer prognosis will be examined in this study in relation to diabetes and glycemic control. Methodology of the study: Researcher performed this cross-sectional study between January 2011 and January 2021 at Galway Hospital, Ireland and University Lahore Teaching Hospital in Lahore, Pakistan. The data was collected from 136 bladder cancer patients during the period of these five years. The data was collected with the permission of ethical committee of hospitals. Patients with last two years of DM were include in this study. Results: The study was completed by 136 patients. Their mean age was 53.2 ± 8.4 years (range: 36-61 years). There were more males than females (60% vs. 40%). Table 1 provides an overview of their clinical and demographic data. Conclusion: Diabetes mellitus is a metabolic condition that affects all main bodily systems, although it is not linked to the advancement of bladder cancer, according to the findings. However, poor glycemic management is linked to a greater recurrence rate. In patients with DM and invasive bladder cancer, glycemic management should be one of the therapy aims.