Abstract
Stress is associated with type 2 diabetes and acute stress could alter glycemic response. Physiological effect of cold pressor stress (CPS; n=40) and control (no CPS; n=43) on glycemic and cardiovascular response to a 50 gram oral glucose tolerance test drink (OGTT) was examined in healthy humans (18±10 years). CPS consisted of three 30‐second left arm ice bath immersions 10 min pre‐OGTT (0 min‐OGTT ingestion), then 10 and 20 minutes post‐OGTT. Blood glucose for control and CPS at ‐15, 0, 30, 60, 120 min was 89.7±9.0, 91.0±8.7, 154.2±21.5, 138.8±32.7, 96.4±19.1 mg/dl and 90.2±7.7, 89.0±6.4, 156.2±21.4, 134.7±24.2, 98.3±21.4 mg/dl respectively (P=0.78). Systolic, diastolic, and mean arterial pressure changes were not statistically significant between treatments. Heart rate diminished across time in both treatments (P= 0.02) although no significant difference was observed between groups. CPS was not associated with significant changes in glycemic and cardiovascular function. However, longer ice bath immersions may promote a greater level of stress that could be associated with altered glycemic response and cardiovascular function.
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