Abstract

Chronic Cd exposure in animals brings about significant morphological and functional changes in both liver and kidney. Most studies of cadmium effects on essential metal tissue distribution involve large concentrations of either Cd or essential metals added to the diet. The effect of Cd ingestion on trace metal metabolism of animals consuming usual diets may be marked, as elements whose physical and chemical properties are enough alike...will act antagonistically to each other biologically. Therefore, the purpose of the present study was to observe the effects of a chronic low dose of Cd added to an otherwise normal diet on the liver and kidney accumulation of zinc, copper, iron, manganese and chromium in the mouse at different times after the cessation of cadmium ingestion.

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