Abstract

Various types of cardiac arrhythmias were induced by local stimulation of the medulla. In studying the effect of chlorpromazine it was revealed that extrasystoles interference with dissociation, and dissociation of the sinus and (heterotropic) ventricular rhythms are arrested by low doses (0.1–0.5 mg/kg body weight). Ventricular paroxysmal tachycardia, dissociation of sinus and ventricular rhythm and disturbance of coronary circulation with an extrasystolic arrhythmia are depressed by high doses of chlorpromazine (1–2.25 mg/kg).

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