Effect of Botox injection in the anterior belly of digastric on skeletal relapse following mandibular advancement surgery. Randomized controlled trial

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Purpose: to test whether Botox injection in the anterior belly of the digastric muscle in sagittal split osteotomy for mandibular advancement could reduce the tendency of postoperative relapse in comparison to the same surgery without Botox injection in bimaxillary orthognathic surgery. Methods: A total of 24 patients indicated for mandibular advancement bi-maxillary orthognathic surgery were randomly assigned to 2 equal parallel groups; 12 patients were injected with Botulinum toxin type A before surgery (Intervention group), and 12 patients were treated without injection (Control group). The relapse was evaluated by the differences in cephalometric variables at 1 week and 6 months postoperatively. The evaluated cephalometric variables are 3 angular measurements (SNB, ANB, and ArGo-SN) and 2 linear measurements (Pog and B point) concerning Frankfort Horizontal and coronal planes on CBCT image. Results: There was a statistically significant difference between the Botox and control groups in Pg/coronal horizontal measurement. The Botox group showed a statistically significant lower increase (lower relapse) in Pg/coronal measurement than the Control group. In comparison between the two groups, there was no statistically significant difference in B and Pg concerning the FH plane, B point about the coronal plane, and all angular measurements: SNB, ANB, and Ar-Go/SN. Conclusion: Botulinum toxin type A injection into the anterior belly of the digastric muscle is an easy and effective approach to decrease relapse following mandibular advancement orthognathic surgery.

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Facial soft tissue changes after maxillary impaction and mandibular advancement in high angle class II cases.
  • Jan 1, 2012
  • International Journal of Medical Sciences
  • Barış Aydil + 2 more

The aim of this study was to determine the vertical and anteroposterior alterations in the soft, the dental and the skeletal tissues associated with the facial profile after Le Fort I maxillary impaction in conjunction with sagittal split osteotomy for mandibular advancement performed in patients with a high angle Class II skeletal deformity.The study population consists of 21 patients (11 females and 10 males, mean age 24.5±1.6 years) who underwent Le Fort I maxillary impaction in conjunction with sagittal split osteotomy for mandibular advancement. Lateral cephalograms were obtained prior to the surgery and 1.3±0.2 years postoperatively. Wilcoxon test was performed to compare the pre- and postsurgical cephalometric measurements. Pearson correlation test was carried out to determine the relative changes in skeletal, dental and the facial soft tissues.The insignificant decrease in the nasolabial angle was correlated with the significant decrease in the vertical position of the nose due to the nasal protraction noticed after bimaxillary surgery. The retraction of both the upper lip and the upper incisors was correlated with the insignificant decrease in the columella-lobular angle. The insignificant decrease in both the vertical height of the mandibular B point and the lower incisors was correlated with the insignificant decrease in vertical height of the soft tissue pogonion, attributable to the resulting superior movement of the soft tissues of the chin and the counter clockwise rotation of the mandible after maxillary impaction and bilateral sagittal split osteotomy, respectively.Le Fort I maxillary impaction in conjunction with mandibular sagittal split osteotomy for mandibular advancement significantly affected the vertical and anteroposterior positions of the maxilla and the mandible, respectively. When performed in combination, these surgical techniques may efficiently alter the position of upper incisor and the nasal position in both vertical and anteroposterior directions. Bimaxillary orthognathic surgery seems to be an efficient method for obtaining satisfactory results in the appearance of the soft, the dental and the skeletal tissues associated with the facial profile in patients with high angle Class II skeletal deformity.

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  • 10.1016/0278-2391(90)90229-u
Causes, location, and timing of relapse following rigid fixation after mandibular advancement
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Causes, location, and timing of relapse following rigid fixation after mandibular advancement

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Evaluation of the effect of bimaxillary, mandibular setback, and advancement surgeries on the pharyngeal airway space and positions of the hyoid bone, soft palate, and tongue
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Introduction: This study aims to assess the postoperative changes in the pharyngeal airway space and the positions of the hyoid bone, soft palate, and tongue after mandibular advancement, mandibular setback, and bimaxillary surgeries. It also aims to compare the effects of mandibular setback and bimaxillary surgeries in the treatment of skeletal Class III patients. Materials and method: Lateral cephalograms of the patients were taken preoperatively and in a period of 3 months postoperatively on 21 subjects (3 groups, 7 patients each) who underwent mandibular setback surgery, bimaxillary surgery for Class III correction, and mandibular advancement surgery, respectively. Pre- and postoperative evaluation of skeletal and soft tissue landmarks were conducted to study the dimensions of the pharyngeal airway space and the position of the hyoid bone, soft palate, and tongue. Results: A significant increase in the oropharyngeal airway was observed after mandibular advancement surgeries, with an uprighting of the soft palate and anterior positioning of the tongue. In the mandibular setback group, the nasopharyngeal airway dimension increased significantly, and the hyoid bone was repositioned posteroinferiorly with posterior movement of the tongue. After bimaxillary surgery in Class III subjects, the nasopharyngeal airway space increased significantly associated with postural changes in the soft palate. Conclusion: Mandibular advancement surgeries can provide conditions for increased airway patency. With regard to the PAS, in Class III patients, maxillary advancement should be preferred to mandibular setback. When mandibular setback is indispensable, the association of movements in bimaxillary surgery can neutralize or minimize the effects of the setback.

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Evaluation of Pharyngeal Airway by Cone-Beam Computed Tomography after Mono- and Bimaxillary Orthognathic Surgery
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Introduction: The aim of this study was to evaluate the changes of the pharyngeal airway obtained using mono-and bimaxillary orthognathic surgery in patients with skeletal malocclusion. Material and Methods: The analysis was conducted on cone-beam computed tomography images taken preoperatively and postoperatively of patients undergoing mono-or bimaxillary orthognathic surgery. The pharyngeal airway was divided into four airway volume segments and measured by planimetry. Results: The bimaxillary surgery group showed an increase in nasopharynx and velopharynx volumes and a decrease in glossopharynx and hypopharynx volumes (P < 0.05). The mandibular setback surgery group showed decreases in glossopharynx, hypopharynx, oropharynx, and pharynx volumes (P < 0.05). The mandibular advancement surgery group showed increases in glossopharynx, hypopharynx, oropharynx, and pharynx volumes (P < 0.05). The maxillary advancement surgery group showed increases in nasopharynx, velopharynx, and pharynx volumes (P < 0.05). Discussion and Conclusion: Mandibular setback surgery had a narrowing effect on the pharyngeal airway volume. Maxillary advancement surgery compensated for the constrictive effect of mandibular setback surgery on both the oropharynx and pharynx volumes. Although maxillary and mandibular advancement surgery affected different sites, these were the operations that contributed most to the increase in pharyngeal volume.

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Class II treatment options broaden
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This study tested the hypothesis that a layperson's social perceptions of a dentofacial deformity (DFD) patient with primary mandibular deficiency (PMD) are more positive after bimaxillary orthognathic surgery.A survey was implemented comparing layperson's social perceptions of emotional expressions and personality traits before and >6 months after orthognathic surgery when viewing standardized facial photographs. The study sample comprised 20 patients selected randomly from a larger primary mandibular deficiency database, treated by 1 surgeon after orthognathic surgery. The outcome variable was change in 6 perceived emotional expressions and 6 personality traits studied. Descriptive and bivariate statistics were computed (P < .05).Five hundred respondents (raters) completed the survey. The respondents were 52% male with 44% aging from 25 to 34. After bimaxillary and chin orthognathic surgery, primary mandibular deficiency patients were perceived to be significantly more dominant, trustworthy, friendly, intelligent, attractive, and less threatening (P < .05). They were also perceived as happier and less angry, surprised, sad, afraid, or disgusted than before surgery (P < .05).Laypeople consistently report improved social traits in primary mandibular deficiency patient's perceived emotional expressions and perceived personality traits after bimaxillary and chin orthognathic surgery.

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Treatment of hyperhidrosis
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  • Research Article
  • Cite Count Icon 12
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Evaluation of the Mandibular Condyle Morphologic Relation before and after Orthognathic Surgery in Class II and III Malocclusion Patients Using Cone Beam Computed Tomography
  • Sep 14, 2022
  • Biology
  • Raluca Roman + 7 more

Simple SummaryIn individuals with severe malocclusions, orthognathic surgery seeks to rebalance the relationships between the jaws by providing a stable occlusion, a healthy muscle balance, and the functioning of the temporomandibular joint. Cone beam computed tomography may be used to determine the position of the mandibular condyle in the glenoid fossa. This study aimed to assess how the position of the mandibular condyle varies in class II and III malocclusions before and after bimaxillary orthognathic surgery. Before and after orthognathic surgery, 56 TMJs from 28 patients were studied. Following surgery, both class II and class III patients experienced changes in the anterior joint space, posterior joint space, condyle position, and condyle angle. The preliminary findings are promising for determining changes in condyle position and joint spaces that might guide oral and maxillofacial surgeons to address a debilitating clinical affliction.This study aimed at evaluating the mandibular condyle position changes before and after bimaxillary orthognathic surgery in class II and III malocclusion patients. CBCT scans from patients who underwent bimaxillary orthognathic surgery were analyzed: Le Fort I osteotomy and bilateral sagittal split osteotomy (BSSO). Both condyles were independently assessed for their largest anterior and posterior joint spaces, smallest medial joint spaces, and condyle angles concerning the transverse line. In the sagittal plane, the minimum size of the anterior and posterior joint spaces was measured. In the coronal plane, the smallest medial joint space was measured. The position of the condyle within the glenoid fossa was determined before and after surgery. A total of 56 TMJs from 28 patients were studied. Following orthognathic surgery, the anterior and posterior space in class II increased. Postoperatively, the anterior joint space in class III decreased. In 42.85% of malocclusion class II patients and 57.14% of malocclusion class III patients, the pre-and post-surgical position of the condyle changed, the condyle was anteriorly positioned (42.85%) in class II patients and centrically positioned (71.4%) in class III patients. Significant changes in the joint space, condylar position, and condyle angle were found in the class II and class III subjects.

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