Abstract
The immunosuppressive effects of blood transfusion in renal transplantation patients are well-known. We investigated as to the relationship between perioperative blood transfusion and survival after surgery of lung cancer. One hundred fifty patients undergoing surgery for lung cancer were analysed retrospectively. The cumulative survival rates for 5 years were 48.8% in those with no transfusion as opposed to 30.2% in those who had been transfused. In patients with Stage I or Stage II and III, transfused patients had lower 5-year-survival rates than nontransfused patients (62.5% versus 69.3% or 6.5% versus 30.8). especially in 71 patients who had undergone lobectomy, the 5-year-survival rate was significantly worse for those who had been transfused (49.8%) than for those who had not been transfused (75.0%) (p<0.05). Therefore perioperative blood transfusion adversely affects prognosis after resection of lung cancer.
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