Effect of Aspirin Consumption on Hematuria and Cardiovascular Complications After Transurethral Resection of Prostate

Abstract

Objectives: This study aimed to evaluate the effects of aspirin on hematuria and cardiovascular events after transurethral resection of the prostate (TURP). Methods: This case-control study was conducted at Sina hospital, an affiliated hospital of Tehran University of Medical Sciences, in 2018. We assessed 132 patients with benign prostatic hyperplasia (BPH) who underwent TURP in two groups (66 patients in each group). In the first group, aspirin was withdrawn 5 - 7 days before the surgery. In the second group, aspirin was given without discontinuation before the surgery. Both groups were followed for 30 days to be compared regarding hematuria, duration of hospitalization, Hb decline rate, the necessity for blood transfusion, secondary hematuria, duration of Foley catheter fixation, and cardiovascular complications after TURP. Results: The duration of Foley catheter fixation, Hb decline rate, and duration of hospitalization were significantly associated with aspirin consumption (P value < 0.05) while blood transfusion, secondary hematuria, and cardiac complications did not correlate with aspirin usage. Conclusions: Aspirin consumption might be a risk factor for Foley catheter fixation duration, blood loss, and length of hospital stay.