Abstract
Obesity is a chronic condition whose incidence is growing due to lack of exercise and frequent nutrition disorders. Childhood obesity has reached epidemic proportions worldwide. One of the best treatment methods is physical training. However, conflicting results have been reported regarding its clinical effectiveness. These contrasting findings may be due to the type and intensity of the adopted physical training program. Therefore, the purpose of the current study was to investigate the effect of an 8-week individualized physical training program on endothelial function, blood biomarkers and adipokine levels in obese adolescents with and without metabolic syndrome (MS). One-hundred-and-twenty-two obese adolescents (71 obese without MS and 51 obese with MS) aged 14 ± 2 years were included in this study. The 8-week individualized training program decreased glucose, triglycerides, total cholesterol, low-density lipoprotein cholesterol and leptin in obese subjects with and without MS. However, adiponectin and endothelial-dependent vasodilatation increased in the follow-up study in both groups. Taken together, the findings suggest that individualized training program is an effective means for the treatment of obesity and MS in pediatric populations.
Highlights
Obesity is a chronic condition whose incidence is growing mostly due to lack of exercise and frequent nutrition disorders [1]
This study examined the effect of an individualized training program on blood biomarkers, This examined effect an training program on blood biomarkers, This study study examined the the effectinof ofobese an individualized individualized training program blood biomarkers, adipokines and endothelial function adolescents with and without
The findings showed that an 8-week individualized training program was able to decrease blood biomarkers and increase adiponectin and endothelial function in both obese adolescents with and without metabolic syndrome
Summary
Obesity is a chronic condition whose incidence is growing mostly due to lack of exercise and frequent nutrition disorders [1]. Childhood obesity has reached epidemic proportions worldwide. In Tunisia, the prevalence of obesity increased more than twofold during the last two decades to reach 22.7% in women, but only 6.4% in men [2]. Cardiovascular risk is frequently associated with obesity in adults and children as well [3] through risk factors, such as increased blood glucose, fasting plasma triglycerides (TG), insulin levels, leptin concentration, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol [4,5]. Res. Public Health 2019, 16, 751; doi:10.3390/ijerph16050751 www.mdpi.com/journal/ijerph
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