Abstract

SummaryThe continuous intravenous injection of adrenal cortical extract to adrenal-ectomized-eviscerate rats improved work output during the faradic stimulation of muscle in one hind leg. There was a concomitant elevation of blood glucose above the level of the untreated rats when the animals continued to work. When both hind legs were stimulated, muscular responsiveness was completely lost in each of the untreated rats within 6 hours and there was an immediate rise in the level of blood glucose above the values for the treated rats which continued to work.

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