Abstract

Angiotensin converting enzyme inhibitors (ACE inhibitors) and angiotensin II receptor inhibitors (ARBs) have been used as standard of care (SoC) for the treatment of diabetes nephropathy (DN) in the United States. Dapagliflozin and saxagliptin have shown to reduce progression of diabetes kidney disease when they are added to the SoC. The present study aimed to determine the cost-effectiveness of dapagliflozin or dapagliflozin plus saxagliptin added to the SoC in diabetes patients with diabetic kidney disease.

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