Abstract

Editorial : Understanding Crohn ’s Disease : Immunity , Genes and Microbes

Highlights

  • Specialty section: This article was submitted to Mucosal Immunity, a section of the journal Frontiers in Immunology

  • Crohn’s disease (CD) and ulcerative colitis (UC) are the two major forms of inflammatory bowel disease (IBD), which has long been characterized as an exacerbated inflammatory response to common antigenic stimuli in the gut due to immune dysregulation

  • While UC is characterized by a diffuse mucosal inflammation involving mainly the rectum and adjacent colonic tissue, CD is a transmural inflammatory disease that may involve any part of the gastrointestinal tract, from the mouth to the anus, in most cases the terminal ileum is affected

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Summary

Introduction

Specialty section: This article was submitted to Mucosal Immunity, a section of the journal Frontiers in Immunology. Editorial on the Research Topic Understanding Crohn’s Disease: Immunity, Genes and Microbes CD and ulcerative colitis (UC) are the two major forms of inflammatory bowel disease (IBD), which has long been characterized as an exacerbated inflammatory response to common antigenic stimuli in the gut due to immune dysregulation.

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