Abstract
Editorial: Transcriptional Regulation of Memory.
Highlights
Laboratory of Synaptic Plasticity and Memory Dysfunction, Division of Neurodegenerative Disorders, Department of Pharmacology and Therapeutics, University of Manitoba, Winnipeg, MB, Canada
Recent data implicate several families of transcription factors and epigenetic processes that appear critical in the regulation of memory
We further acknowledge the importance of transcriptional processes for both memory consolidation and reconsolidation, and recognize there are still a lot of unanswered questions: For example, what are the key transcription factors involved in the regulation of memory? What are their gene targets and how do they mediate memory formation? How is transcription regulated over time? How does epigenetics contribute to memory? Can the context or our experience influence the pattern of transcription and regulate the formation of memory?
Summary
The formation of human memories involves a series of complicated biochemical processes, many of which are not fully understood. Recent data implicate several families of transcription factors and epigenetic processes that appear critical in the regulation of memory. We further acknowledge the importance of transcriptional processes for both memory consolidation and reconsolidation, and recognize there are still a lot of unanswered questions: For example, what are the key transcription factors involved in the regulation of memory?
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