Abstract
Editorial: Protein Interaction Networks in Health and Disease.
Highlights
The identification and annotation of protein-protein interactions (PPIs) is of great importance in systems biology
We present methods for the identification and quantification of PPIs; second, we describe computational approaches to annotate interactomes and extract information related to disease prediction or disease progression
Authors present an accurate method to analyze yeast two-hybrid data by next generation sequencing (NGS) and interpret interaction data via quantitative statistics. They discuss how this methodology can be used to discover differential PPIs allowing the identification of disease mechanisms (Suter et al.)
Summary
The identification and annotation of protein-protein interactions (PPIs) is of great importance in systems biology. Protein Interaction Networks in Health and Disease (2016) Editorial: Protein Interaction Networks in Health and Disease.
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