Abstract

Since December 2019, when the initial cases of severe viral pneumonia caused by a new coronavirus were described, health services worldwide have sought to understand the evolution and risk factors related to the severity of coronavirus disease (COVID-19). Elderly individuals have been shown to be the highest risk group. However, other factors, such as male sex; obesity; smoking; and chronic heart, lung, kidney, and liver diseases, are also associated with a poor prognosis. We draw attention to immunosuppressed patients as [...]

Highlights

  • Since December 2019, when the initial cases of severe viral pneumonia caused by a new coronavirus were described, health services worldwide have sought to understand the evolution and risk factors related to the severity of coronavirus disease (COVID-19)

  • We report on a severe presentation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in a 37-year-old male patient with cystic fibrosis (CF) in the second week after lung transplantation (LTx)

  • He had a good clinical outcome without the use of antivirals or immunomodulatory drugs. He was weaned off invasive mechanical ventilation on post-operative day (POD) 19 and was discharged from the intensive care unit on POD 23. He presented with progressive clinical and radiological improvement (Figure 1B) in the ward and was discharged from hospital on POD 39, he still tested positive on SARS-CoV-2 polymerase chain reaction (PCR) tests at 15 and 25 days after symptom onset

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Summary

Introduction

We draw attention to immunosuppressed patients as they are a vulnerable group with a high susceptibility to severe forms of the disease [1,2]. We report on a severe presentation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in a 37-year-old male patient with cystic fibrosis (CF) in the second week after lung transplantation (LTx). He presented with progressive clinical and radiological improvement (Figure 1B) in the ward and was discharged from hospital on POD 39, he still tested positive on SARS-CoV-2 PCR tests at 15 and 25 days after symptom onset.

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