Abstract
Dyslipidemia, a major risk factor for cardiovascular diseases, has become a global issue. Due to the variations in the prevalence of dyslipidemia, this study aimed to evaluate dyslipidemia and its associated factors in women of the Bandare-Kong Cohort Study (BKNCD). This study was conducted on women from the population-based BKNCD, as part of the Prospective Epidemiological Research Studies in IrAN (PERSIAN). Sociodemographic data, medical history, and anthropometric indices were collected. Dyslipidemia was defined as any lipid abnormality including low-density lipoprotein (LDL) ≥ 160, total cholesterol (TC) ≥ 240, high-density lipoprotein (HDL) < 40, or triglyceride > 200 mg/dl. From the 2223 women in this study (mean age: 48.28 ± 9.26 years), dyslipidemia was observed in 851 (38.3%). High TC was the most common lipid abnormality (18.5%) followed by high LDL (17.7%). Dyslipidemia was most prevalent among women aged 55–70 years, the married, those with < 6 years of education, the unemployed, the overweight or obese, with low socioeconomic status, diabetes, hypertension, and high waist circumference, those using the hookah and living in urban areas. Logistic regression revealed that women with high waist-to-hip ratio (WHR) (OR = 2.22, 95% CI 1.60–3.08), those aged 45–54 years (OR = 1.34, 95% CI 1.07–1.68) and 55–70 years (OR = 1.33, 95% CI 1.03–1.72), and those living in urban areas (OR = 1.35, 95% CI 1.05–1.73) were at significantly increased risk of dyslipidemia. In addition, the results were confirmed using deep neural network models. Dyslipidemia was highly prevalent in Iranian women in the southern coastal region. Central obesity, age over 45 years, and living in urban areas appear to be relatively significant risk factors for dyslipidemia among women.
Highlights
Dyslipidemia, a major risk factor for cardiovascular diseases, has become a global issue
There is no information about the women who live in the southern coastal of Iran, we aimed to evaluate dyslipidemia and its associated factors in women of the Prospective Epidemiological Research Studies in IrAN (PERSIAN) Bandare-Kong Cohort Study
High TG, high total cholesterol (TC), low high-density lipoprotein (HDL), and high low-density lipoprotein (LDL) were exclusively seen in 3.5%, 1.9%, 10.8%, and 2.3%, respectively
Summary
Dyslipidemia, a major risk factor for cardiovascular diseases, has become a global issue. Dyslipidemia was defined as any lipid abnormality including low-density lipoprotein (LDL) ≥ 160, total cholesterol (TC) ≥ 240, high-density lipoprotein (HDL) < 40, or triglyceride > 200 mg/ dl. Dyslipidemia was most prevalent among women aged 55–70 years, the married, those with < 6 years of education, the unemployed, the overweight or obese, with low socioeconomic status, diabetes, hypertension, and high waist circumference, those using the hookah and living in urban areas. LDL Low-density lipoprotein MET Metabolic equivalent of task OR Odds ratio PERSIAN Prospective Epidemiological Research Studies in IrAN ROC Receiver operating characteristic SBP Systolic blood pressure SES Socioeconomic status SPSS Statistical Package for the Social Sciences TC Total cholesterol TG Triglyceride WC Waist circumference WHO World Health Organization WHR Waist-to-hip ratio. According to the World Health Organization (WHO) estimates, dyslipidemia, especially high TC, is responsible for 2.6 million deaths annually and 29.7 million disability-adjusted life years (DALYS) w orldwide[4]
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