Abstract

We present the model of tumour induced angiogenesis that apart from predominating phenomena, as influence of VEGF, includes newly discovered factors such as Dll4/Notch signalling and remodelling processes. The Cellular Automata approach is employed to model cellular and intracellular processes that occur in cancer tissue and surroundings. Vascular system is modelled by using the Graph of Cellular Automata, which combines graph theory with the Cellular Automata paradigm. Additionally, an outline of model verification method which uses graph descriptors is presented and exemplified.

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