Abstract
The hierarchical organization of the chromatin fiber, the functional form of DNA in cells, has been extensively studied from a single nucleosome to the genome-wide scale. Chromosome conformation capture techniques revealed a detailed static picture of the genome's 3D folded state inside the cell nucleus, revealing presence of loops, topologically associated domains, A/B compartments and chromosome territories [1]. In addition, chromatin organization was found to resemble a fractal globule inside the nucleus [2].
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