Abstract
Since typhoid fever continues to be a major health problem in developing countries emphasis is on for search of a simple rapid as well as sensitive and specific test/s which can be used in peripheral health services. Various serological test/s had been devised to detect antibodies and antigens of Salmonella enterica Serovar Typhi in the past. Ismail et al. detected a 50 kDa outer membrane protein (OMP) specific for the serotype Typhi and further evaluated the antigen using dot enzyme-immunoassay (EIA) format and observed that this antigen could react with Salmonella typhi-specific IgM and IgG in sera from patients with acute typhoid fever. Jesudason et al. reported Typhidot to be 100% sensitive and 80% specific with respect to blood culture a study from southern part of India. In the present study we performed dot EIA IgM and IgG (Typhidot) along with nested PCR Widal test and blood culture in eight pediatric patients (aged 1-12 years) which were suspected cases of acute typhoid fever in an endemic area. (excerpt)
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
