Abstract
ELIMED has been developed and installed at ELI beamlines as a part of the ELIMAIA beamline to transport, monitor, and use laser-driven ion beams suitable for multidisciplinary applications, including biomedical ones. This paper aims to investigate the feasibility to perform radiobiological experiments using laser-accelerated proton beams with intermediate energies (up to 30 MeV). To reach this goal, we simulate a proton source based on experimental data like the ones expected to be available in the first phase of ELIMED commissioning by using the G4-ELIMED application (an application based on the Geant4 toolkit that simulates the full ELIMED beamline). This allows the study of transmission efficiency and the final characteristics of the proton beam at the sample irradiation point. The Energy Selector System is used as an active energy modulator to obtain the desired beam features in a relatively short irradiation time (around 6 min). Furthermore, we demonstrate the capability of the beamline to filter out other ion contaminants, typically co-accelerated in a laser-plasma environment. These results can be considered as a detailed feasibility study for the use of ELIMED for various user applications such as radiobiological experiments with ultrahigh dose rate proton beams.
Highlights
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The characteristics of the laser-accelerated ion beam will depend on the used laser and target parameters
ELIMED’s absolute dosimetry systems are independent of the ultra-high dose rate and allow to perform online absolute dose determination with an accuracy better than 5%, satisfying the internationally established clinical requirements [13,14,15]
Summary
Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. High power laser-plasma interaction is a new and innovative approach to produce and accelerate particle beams [1]. The interaction of ultrahigh laser intensities (>1019 W/cm ). With a thin (~μm) solid target results in the generation of extremely high magnetic and electric fields that produce a plasma and relativistic electrons (known as “hot electrons”). Propagating into the vacuum and creating a quasi-static sheath electric field at the targetvacuum interface. Such a field ionizes the target rear side and accelerates the ions outwards. The characteristics of the laser-accelerated ion beam will depend on the used laser and target parameters
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