Abstract
This study tested the capacity of different irradiances of monochromatic light to reduce plasma melatonin in normal humans. Six healthy male volunteers, 24–34 years old, were exposed to 0.01, 0.3, 1.6,5, or 13 μW/cm 2 of 509 nm monochromatic light for 1 h during the night on separate occasions. Light irradiance depressed plasma melatonin in a dose-response pattern. The data indicate that the mean threshold irradiance for suppressing melatonin is between 1.6 and 5μW/cm 2. Individual variations in threshold responses to monochromatic light were observed among the volunteers.
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