Donor-specific transfusion via the portal venous route induces prolongation of H-2-compatible but not H-2-incompatible cardiac graft survival

D Górecki,J Czyźyk,M Łupińska,A Kruszewski,M Jakóbisiak

doi:10.1007/bf02414534

Donor-specific transfusion via the portal venous route induces prolongation of H-2-compatible but not H-2-incompatible cardiac graft survival

D Górecki, J Czyźyk + Show 3 more

https://doi.org/10.1007/bf02414534

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Journal: Transplant International	Publication Date: Dec 1, 1989
Citations: 13

#Donor-specific Blood Transfusion #Donor-specific Transfusion + Show 8 more

Abstract
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Abstract

In the H-2-compatible donor-recipient combination (BALB/c----DBA/2), pretransplant donor-specific blood transfusion (DST) via the portal venous (PV) route significantly prolonged cardiac graft survival. DST via the intravenous (IV) route (systemic circulation) also showed a marked prolongation of heart tissue transplant survival in this model. In the H-2-incompatible combination (BALB/c----CBA/H), DST via the IV - but not via the PV - route resulted in accelerated graft rejection.

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