Abstract

As a potential complication of a systemic administration of cytotoxic agents, extravasation requires particular caution of all health practitioners involved in treatments of oncological patients. In the light of the fact that more than 100.000 doses of chemotherapy are indicated worldwide and more than 1.000.000 intravenous infusion of cytostatic drugs are administered on daily bases, it is upsetting that in the case of cytostatic administration through peripheral intravenous cannulas extravasation occurs in 0,5 to 6% of oncological patients, while in the case of administration through central venous lines it occurs in 6% of the cases. Each extravasation results in tissue damage and depending on type and features of the administered substance can be manifested in different forms, from skin reaction to tissue necrosis. By highlighting the multiple significance of documenting and accident reporting, the authors state the necessary elements and propose the form of a nurse documenting list for the cases of extravasation of cytostatic agents. A nurse must document the following data on an accident: patient's name and surname, date of birth, name of the clinics, primary oncological diagnosis, date and time of extravasation, name of the cytotoxic drug, symptoms and signs of extravasation and the measures undertaken. The accurate documenting and reporting of accidents are legally binding for health practitioners, particularly nurses, as a result of the need to map the risk factors of their occurrence, to assess compliance of the standard nursing procedures in administration of cytostatic therapy, to follow up the course of the management of complications, outcomes and the undertaken measures but also to improve the existing and develop new preventive strategies.

Highlights

  • As a potential complication of a systemic administration of cytotoxic agents, extravasation requires particular caution of all health practitioners involved in treatments of oncological patients

  • Rano prepoznavanje i pravovremeno reagovanje zdravstvenih radnika u slučaju ekstravazacije citostatika od izuzetne je važnosti u tretmanu pacijenata sa aplikovanom hemioterapijom [1,6]

  • Tabela 2: Podela antineoplastičnih lekova prema posledicama koje izazivaju u slučaju ekstravazacije ustaljena u Velikoj Britaniji

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Summary

DOCUMENTING OF EXTRAVASATION OF CYTOTOXIC AGENTS

APSTRAKT Kao potencijalna komplikacija sistemske primene citotoksičnih agenasa ekstravazacija zahteva posebnu pažnju svih zdravstvenih radnika uključenih u tretman onkoloških pacijenata. U svetlu činjenice da se u svetu, na dnevnom nivou, indikuje više od 100.000 doza hemioterapije i aplikuje više od 1.000.000 intravenskih infuzija citostatika, zabrinjava podatak da se u slučaju primene citostatika preko perifernih intravenskih kanila ekstravazacija registruje kod 0,5% do 6% onkoloških pacijenata, a preko centralnih venskih linija u 6% slučajeva. Potencirajući višestruki značaj dokumentovanja i prijave akcidenta, autori navode neophodne elemente i predlažu formu sestrinskog dokumentacionog lista u slučajevima ekstravazacije citostatika. Pravilno dokumentovanje i prijava akcidenta predstavljaju zakonsku obavezu zdravstvenih radnika, prvenstveno medicinskih sestara, proisteklu iz potrebe mapiranja faktora rizika za njegovu pojavu, procene poštovanja standardnih sestrinskih procedura u primeni citostatske terapije, praćenja toka zbrinjavanja nastale komplikacije, ishoda preduzetih mera, ali i unapređenja postojećih i razvijanja novih preventivnih strategija.

ORIGINAL ARTICLE
FAKTORI RIZIKA ZA EKSTRAVAZACIJU CITOSTATIKA
SIMPTOMI I ZNACI EKSTRAVAZACIJE CITOTOKSIČNIH AGENASA
Findings
INICIJALNI TRETMAN PACIJENTA U SLUČAJU EKSTRAVAZACIJE CITOTOKSIČNIH AGENASA
Full Text
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