Abstract
Use of combination antiretroviral therapy during pregnancy has lowered perinatal HIV transmission rates to less than 2% in the U.S. Nonetheless, concerns exist about the risk for preterm delivery. In European cohorts, this risk was significantly higher with combination therapy, with or without PIs, than with no therapy ( AIDS 2000; 14:2913). However, in a large study of seven U.S. cohorts, there was no increase in risk with any type of antiretroviral therapy (ACC Sep 1 2002). To evaluate this issue further, …
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