Abstract
J.C. Wang, DNA Topoisomerases as Targets of Therapeutics: An Overview. Y.-C. Tse-Dinh, Biochemistry of Bacterial Type I DNA Topoisomerases. R. Menzel and M. Gellert, The Biochemistry and Biology of DNA Gyrase.J.J. Champoux, Mechanism of Catalysis by Eukaryotic DNA Topoisomerase I. A.H. Andersen, J.Q. Svejstrup, and O. Westergaard, The DNA Binding, Cleavage, and Religation Reactions of Eukaryotic Topoisomerases I and II. J.L. Nitiss, Roles of DNA Topoisomerases in Chromosomal Replication and Segregation. M. Drolet, H.-Y. Wu., and L.F. Liu, Roles of DNA Topoisomerases in Transcription. H. Ikeda, DNA Topoisomerase-Mediated Illegitimate Recombination. J. Hwang and C.-L. Hwong,Cellular Regulation of Mammalian DNA Topoisomerases. T.-s. Hsieh, M.P. Lee, and S.D. Brown, Structure of Eurkaryotic Type I DNA Topoisomerase. W.M. Huang, Type II DNA Topoisomerase Genes. H.C. Neu, Major Advances in Antibacterial Quinolone Therapy. K. Drlica and B. Kreiswirth, 4-Quinolones and the Physiology of DNA Gyrase. L.L. Shen, Molecular Mechanisms of DNA Gyrase Inhibition by Quinolone Antibacterials. References. Subject Index.
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