Abstract

Lead is one of the most clinically important heavy metals, because it induces a broad range of physiological,biochemical, and genetical dysfunctions. Occupational exposure to lead leads to increased frequency of genetic systemin human beings. In the present study the DNA damage among the workers occupationally exposed to lead wasanalyzed using peripheral blood lymphocyte by comet assay. The result of this study shows increased levels of DNAdamage among experimental subjects. The habit of cigarette smoking among the workers has a synergistic effect oninducing DNA damage.

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