Abstract
Abstract : In five unanaesthetized trained dogs the effect of injection of small quantities of water into a carotid loop on the excretion of urine was investigated. The infusion rates were 3.0, 2.5 and 2.0 ml/min. Infusion time was 30 min, so that a total of 90, 75 and 60 ml of water was injected. As controls, identical water infusions were made into a peripheral vein. The following results were obtained: Diuresis occurred only with intracarotid infusions. This speaks in favour of a central location of osmoreceptors. The diuresis was a function of the amount of water infused and was due solely to an increase in free water clearance. The excretion of electrolytes and the osmotic clearance remained unchanged. These findings can best be explained by the ADH mechanism. (Author)
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
