Abstract
BackgroundThe risk factors for ischemic stroke in young people are complex, varied and closely related to prognosis. This study aims to analyze the risk factors for ischemic stroke in Chinese young people and to explore the main factors influencing the prognosis.MethodA total of 444 patients aged 16 to 45 years with ischemic stroke admitted to Suzhou tertiary hospital from 2011 to 2019 were retrospectively analyzed. Risk factors were identified according to the IPSS definition of pediatric stroke and the TOAST classification. All patients were followed up, and the modified Rankin score was used to evaluate the prognosis. Logistic regression analysis was used to explore the influencing factors of poor prognosis.ResultsAmong the patients, 12 risk factors were found according to the IPSS definition of pediatric stroke, and 5 types of stroke were found according to the TOAST classification. A total of 299 patients had a good prognosis. Anemia, venous sinus thrombosis, isolated large-vessel occlusion, and high baseline NIHSS score were significant risk factors.ConclusionThe IPSS definition enables patients to be classified on the basis of more risk factors than other classification methods. The prognosis of ischemic stroke in young people is generally good in the 5 years following the event. Anemia, venous sinus thrombosis, isolated large-vessel occlusion and high baseline NIHSS score were associated with poor prognosis.
Highlights
Stroke has become a major disease threatening life and health worldwide and is a major global public health problem to be solved [1].The latest epidemiological studies show that the age-specific incidence of stroke is becoming increasingly younger [2]
Among the patients, 12 risk factors were found according to the IPSS definition of pediatric stroke, and 5 types of stroke were found according to the TOAST classification
The prognosis of ischemic stroke in young people is generally good in the 5 years following the event
Summary
Stroke has become a major disease threatening life and health worldwide and is a major global public health problem to be solved [1].The latest epidemiological studies show that the age-specific incidence of stroke is becoming increasingly younger [2]. Ischemic stroke in youth refers to ischemic stroke in individuals younger than 45 years old [3]. Wu et al BMC Neurology (2022) 22:26 followed up for an average of 4.763 ± 0.96 years, with the objective to investigate the prognosis of young patients with ischemic stroke, to explore the risk factors affecting their prognosis, and to provide a reference for the individualized prevention and treatment of ischemic stroke in young patients. This study aims to analyze the risk factors for ischemic stroke in Chinese young people and to explore the main factors influencing the prognosis
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