Abstract

Objective: To understand the distribution of drug susceptibility test results of opportunistic infections of tuberculosis and non-tuberculous bacilli in AIDS patients. Methods: The AIDS patients who were hospitalized in our hospital from January 2016 to June 2019 were collected as the research objects, and patients with opportunistic tuberculosis and non-tuberculous bacilli from AIDS patients were screened for drug susceptibility tests, and the distribution characteristics of drug susceptibility were analyzed. Results: 179 strains of tuberculosis and non-tuberculous mycobacteria were isolated from the specimens of AIDS patients, including 135 cases of tuberculosis mycobacteria and 44 cases of non-tuberculous mycobacteria. In the results of the drug susceptibility test, most strains of Mycobacterium tuberculosis showed sensitivity to commonly used drugs, and a few strains showed resistance; most strains of non-tuberculous mycobacteria showed resistance, and a few strains showed sensitivity. Conclusion: AIDS opportunistic infection of Mycobacterium tuberculosis and non-tuberculous mycobacteria have significant differences in drug sensitivity test results. Timely detection and analysis are of great significance to the diagnosis and treatment of the disease.

Highlights

  • The AIDS patients who were hospitalized in our hospital from January 2016 to June 2019 were collected as the research objects, and patients with opportunistic tuberculosis and non-tuberculous bacilli from AIDS patients were screened for drug susceptibility tests, and the distribution characteristics of drug susceptibility were analyzed

  • AIDS opportunistic infection is a secondary pathogen infection that occurs because people are infected with AIDS virus, which leads to low immunity of the body [1]

  • AIDS has a higher chance of opportunistic infection of Mycobacterium tuberculosis complex and non-tuberculous mycobacteria

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Summary

Introduction

AIDS opportunistic infection is a secondary pathogen infection that occurs because people are infected with AIDS virus, which leads to low immunity of the body [1]. For people with normal immunity, these pathogen infections rarely occur. AIDS patients have reduced immunity and are prone to opportunistic infections with these pathogens. Once infected, they will aggravate the disease and cause various complications and endanger life, even death [2] [3]. When HIV infection is diagnosed, it is necessary to assess the condition in time to determine whether there is opportunistic pathogen infection [4]. If there is a relevant opportunistic infection, it is necessary to formulate a corresponding treatment plan in time

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