Abstract
AbstractA line sampling method was used to determine the relative volumes of various cell types in the mucosa of the body of the rat stomach. The technique was simple to perform, reproducible and independent of many variables inherent in previous cell counting techniques. Weights of the various cell types were calculated from stomach weights, relative mucosal volumes and cell concentrations in the mucosa. In the five animals studied, gastric body mucosa average 40% of the stomach weight and 1.8 gm per kg of rat. Parietal cells averaged 40% of the gastric body mucosa weight and 0.7 gm per kg of rat. There was no significant variation in parietal cell concentration throughout the gastric body mucosa of the rat. Chief cells averaged 18% of the gastric body mucosa and 0.3 gm per kg of rat. Up to three‐fold variations in chief cell concentration occurred with highest concentrations near the greater curvature and in proximal areas of the body mucosa. Mucous surface cells, mucous neck cells, and connective tissue made up 22, 9, and 7% of the body mucosa respectively and showed only minor varitions in concentration.
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