Distinguishing actual from 3D-printed bite marks in forensic odontology: accuracy and reliability of digital analysis.

Recent advances in 3D printing technologies for wearable (bio)sensors

Split-Rib Cranioplasty Using a Patient-Specific Three-Dimensional Printing Model

Advances in areas such as data analytics, genomics, and imaging have revealed individual patient complexities and exposed the inherent limitations of generic therapies for patient treatment. These observations have also fueled the development of precision medicine approaches, where therapies are tailored for the individual rather than the broad patient population. 3D printing is a field that intersects with precision medicine through the design of precision implants with patient-directed shapes, structures, and materials or for the development of patient-specific in vitro models that can be used for screening precision therapeutics. Toward their success, advances in 3D printing and biofabrication technologies are needed with enhanced resolution, complexity, reproducibility, and speed and that encompass a broad range of cells and materials. The overall goal of this progress report is to highlight recent advances in 3D printing technologies that are helping to enable advances important in precision medicine.

Pharmaceutical 3D printing has become a revolutionary technique that is revolutionizing drug research, personalized treatment, and medication delivery methods. This article examines how accurate dosing, complicated drug delivery methods, and personalized drug formulations are made possible by 3D printing, which helps the pharmaceutical sector overcome major obstacles. 3D printing opens the door to more efficient and patient-specific treatments by personalizing therapies and accelerating the development process. The purpose of this study is to explore the potential applications of current 3D printing technologies in drug delivery, personalized medicine, and pharmaceutical sciences to enhance treatment results and patient care. The latest advancements in 3D printing technology utilized in the pharmaceutical sector were thoroughly examined. The main techniques studied are fused deposition modelling (FDM), stereolithography (SLA), and selective laser sintering (SLS), with a focus on their usage in the production of drug delivery devices, customized dosage forms, and bioprinted tissues. The study also looked at a range of materials, i.e., hydrogels, bioinks, and polymers, to assess their suitability for use in pharmaceutical applications. The findings demonstrate significant advancements in the creation of customized pharmaceutical formulations which may be 3D printed to allow for exact dosages and modified release patterns. Additionally, bioprinting has demonstrated promise in regenerative medicine and tissue engineering. 3D printing is speeding up the creation of intricate drug delivery systems, like implants and patches, which improve treatment results and patient adherence in spite of technological and legal obstacles. This study highlights the transformative role of 3D printing in pharmaceutical sciences, particularly in enabling personalized medicine and advanced drug delivery systems. 3D printing techniques like FDM, SLA, and SLS have shown promising applications in producing customized dosage forms and complex drug delivery devices. The ability to tailor medications to individual patient needs enhances therapeutic outcomes and minimizes side effects. 3D printing has emerged as a potential tool in regenerative medicine and patient-specific solutions. Pharmaceutical 3D printing offers ground-breaking potential for customized treatment and medication creation. It enables the development of solutions that are tailored to the requirements of every patient, increasing therapeutic efficacy and minimizing adverse effects. Even if there are still issues, mainly with scalability and regulatory compliance, continuous improvements in materials and technology hold out the possibility of growing its use in healthcare. With its patient-centered, effective, and creative pharmaceutical production options, 3D printing is set to revolutionize the medical field. This study presents a current advancement in 3D printing technologies with their emerging applications in drug delivery, personalized medicine, and pharmaceutical sciences, highlighting innovative, patient-specific therapeutic solutions.

Advancements in 3D printing technology are providing a new direction in pediatric dentistry by offering innovative solutions to traditional challenges. The remarkable expansion of 3D printing necessitates a comprehensive examination of its status and applications in the dental field, particularly in the pediatric dentistry. This review provides a comprehensive exploration of the applications of 3D printing in pediatric dental practices by drawing from a systematic search across databases, including PubMed/MEDLINE, Scopus, Web of Science, Scielo and the Cochrane Library. The search strategy employed a combination of keywords: "Digital dentistry and 3D printing", "3D printing technology in dentistry", "3D printing in pediatric dentistry" and "3D printing in pediatric dental procedures". The review encompasses a wide array of studies, including original research, cross-sectional analyses, case reports and reviews. A detailed overview is presented in regard to the use of 3D printing for master and educational models, space maintainers, prosthetic restorations, surgical guide, splint design and fracture treatment, fluoride application, autogenous dental transplantation, anterior teeth restoration, and pediatric endodontics and regenerative treatments. This review shows that 3D printing improves clinical outcomes through personalized and precise treatment options and enhances dental students' educational landscape. Areas lacking extensive research were also identified, which warrent further investigation to optimize the integration of 3D printing in pediatric dentistry. By mapping out the current landscape and future directions, the aim of this paper is to support pediatric dentists in recognizing the broad implications of 3D printing for improving patient care and advancing dental education.

To review the use of three-dimensional (3D) printing in facial plastic and reconstructive surgery, with a focus on current uses in surgical training, surgical planning, clinical outcomes, and biomedical research. To evaluate the limitations and future implications of 3D printing in facial plastic and reconstructive surgery. Studies reviewed demonstrated 3D printing applications in surgical planning including accurate anatomic biomodels, surgical cutting guides in reconstruction, and patient-specific implants fabrication. 3D printing technology also offers access to well tolerated, reproducible, and high-fidelity/patient-specific models for surgical training. Emerging research in 3D biomaterial printing have led to the development of biocompatible scaffolds with potential for tissue regeneration in reconstruction cases involving significant tissue absence or loss. Major limitations of utilizing 3D printing technology include time and cost, which may be offset by decreased operating times and collaboration between departments to diffuse in-house printing costs SUMMARY: The current state of the literature shows promising results, but has not yet been validated by large studies or randomized controlled trials. Ultimately, further research and advancements in 3D printing technology should be supported as there is potential to improve resident training, patient care, and surgical outcomes.

Using 3D printer technology to advance and optimize the use of bolus in the radiotherapy workflow

The field of 3D printing is in rapid evolution. The 3D printing technology applied to civil engineering is a promising advancement. From equipment and mixture design to testing methods, new developments are popping up to respond to specific demands either for the fresh or hardened state. Standardizing methods are still at an early age. For this reason, there is a multitude of 3D printers with different capabilities to print cementitious materials. In addition, norms are not applicable in 3D printing material science. Advances are being made to create new methods of testing. The key parameters of this new 3D printing process based on stratification, multiple uses of binders, and measurement at fresh and hardened states are being perfected to achieve an industrial application. This article gives an overview of how 3D-printed structures are made along with critical parameters that influence their performances. Our review suggests that the quality of the 3D prints is determined by the printing method, key printing parameters, and the mix design. We list different tests to help characterize these 3D-printed cementitious materials at the fresh state and to assess their performances at the hardened state. We aim throughout this work to give a state-of-the-art of recent advances in 3D printing technology. This could help for a better understanding of cementitious materials 3D printing for current and future related research work.

Diabetic foot ulcers (DFUs) are a serious complication of diabetes mellitus (DM), affecting around 25% of individuals with DM. Primary treatment of a DFU involves wound off-loading, surgical debridement, dressings to provide a moist wound environment, vascular assessment, and appropriate antibiotics through a multidisciplinary approach. Three-dimensional (3D) printing technology is considered an innovative tool for the management of DFUs. The utilization of 3D printing technology in the treatment of DFU involves the modernization of traditional methods and the exploration of new techniques. This review discusses recent advancements in 3D printing technology for the application of DFU care, and the development of personalized interventions for the treatment of DFUs. We searched the electronic database for the years 2019-2024. Studies related to the use of 3D printing technology in Diabetic foot were included. A total of 25 identified articles based on database search and citation network analysis. After removing duplicates, 18 articles remained, and three articles that did not meet the inclusion criteria were removed after reading the title/abstract. A total of 97 relevant articles were included during the reading of references. In total, 112 articles were included. 3D printing technology offers unparalleled advantages, particularly in the realm of personalized treatment. The amalgamation of traditional treatment methods with 3D printing has yielded favorable outcomes in decelerating the progression of DFUs and facilitating wound healing. However, there is a limited body of research regarding the utilization of 3D printing technology in the domain of DFUs.

A comparative study between xerographic, computer-assisted overlay generation and animated-superimposition methods in bite mark analyses.

Background and ObjectiveAnterior lumbar interbody fusion (ALIF) is a safe and effective type of lumbar interbody fusion (LIF) technique. Each LIF technique requires implants specifically designed to accommodate its distinct anatomical corridor and dimensional constraints. This narrative review is about the implants used for ALIF. Specifically, what materials are used to create the implants, and how those properties collectively contribute to arthrodesis. It also summarizes the role of additive manufacturing, also known as 3D printing, in the creation of the next generation of ALIF implants.MethodsRelevant articles were identified through a comprehensive search of PubMed and Google Scholar, using keywords like “Anterior Lumbar Interbody Fusion (ALIF)”, “ALIF Implants”, “3D-Printed Implants”, “Medical Applications of 3D Printing”, “Off-the-Shelf (OTS) Implants”, “Patient-Specific Implants”. Only peer-reviewed, English-language publications discussing implant materials, properties, or 3D printing integration for ALIF were included.Key Content and FindingsTitanium and polyetheretherketone (PEEK) are the primary materials used in ALIF implants. Recent advances in 3D printing technology can create implants with specific design features previously unattainable with conventional methods, which can improve their overall durability and utility. These 3D-printed implants can be customized in terms of porosity, stiffness, and surface texture to promote fusion, increase implant longevity, and support indirect decompression. 3D printed patient-specific implants are now available. Implants are built to specifically match the computed tomography or magnetic resonance imaging rendering of the patient’s anatomy.ConclusionsALIF is a safe and effective procedure for patients with appropriate indications. The anatomical corridor utilized in ALIF allows for the placement of implants with a large footprint, which, along with specific implant properties, contributes to the high fusion rates associated with this technique. Advances in 3D printing technology now enable the production of titanium and PEEK ALIF implants with enhanced design features, further improving the procedure’s safety and efficacy profile.

We aimed to explore the application of three-dimensional (3D) printing technology with problem-based learning (PBL) teaching model in clinical nursing education of congenital heart surgery, and to further improve the teaching quality of clinical nursing in congenital heart surgery. In this study, a total of 132 trainees of clinical nursing in congenital heart surgery from a grade-A tertiary hospital in 2019 were selected and randomly divided into 3D printing group or traditional group. The 3D printing group was taught with 3D printed heart models combined with PBL teaching technique, while the traditional group used conventional teaching aids combined with PBL technique for teaching. After the teaching process, the 2 groups of nursing students were assessed and surveyed separately to evaluate the results. Compared to the traditional group, the theoretical scores, clinical nursing thinking ability, self-evaluation for comprehensive ability, and teaching satisfaction from the questionnaires filled by the 3D printing group were all higher than the traditional group. The difference was found to be statistically significant (P < .05). Our study has shown the 3D printing technology combined with the PBL teaching technique in the clinical nursing teaching of congenital heart surgery achieved good results.

P135. Radiological outcomes of a novel 3-dimensional printed titanium cervical interbody cage following single and multilevel anterior cervical discectomy and fusion: a case series of 108 operated levels

2 - Applications of 3D printing for the advancement of oral dosage forms

The widespread use of digital imaging can now be combined with additive three-dimensional (3D) printing, changing traditional clinical dentistry, especially in challenging cases. Visualizing the bone and soft tissue anatomy using computed tomography (CT) and intraoral scanning generated digital files that can be further processed for 3D printing. Among the popular 3D printing approaches, fused filament fabrication (FFF) and stereolithography (SLA) are broadly used due to their rapid production, precision, and ease of use. The current case series outlines three challenging clinical scenarios where a combination of CT and intraoral scans were utilized for digital planning. FFF multicolor anatomical models and SLA surgical guides were produced using 3D printing technology. The first case outlines the utility of this approach to place the optimal surgical window at the lateral sinus lift with anticipated difficult access. In the second case, distinct sites for autogenous bone harvesting were identified while preserving critical adjacent structures with surgical simulation. Finally, the third case outlines this strategy for optimal surgical access to expose an impacted second premolar. Both clinicians and patients benefited from the educational use of FFF‒SLA 3D-printed models, and all cases were successfully treated without complications. These cases demonstrate the significant utility of these digital technologies and rapid prototyping for improved pre-surgical planning, patient motivation, and didactic training that contribute to improved quality of clinical care. To the authors' knowledge, this is the first case reports employing both fused filament fabrication (FFF) and stereolithography (SLA) printing techniques in dental surgery. This innovative approach addresses a range of clinically challenging scenarios presented in this report. Computed tomography (CT) and intraoral scanning are essential for three-dimensional (3D) reconstruction. Specialized software is required to design the guide with precise specifications, and FFF and SLA printers are necessary for fabricating the 3D model. Three-dimensional reconstruction can be time-intensive, particularly when manual segmentation is necessary. Acquiring proficiency in the software may require additional time, and multicolor 3D printing also demands extended printing durations. This study explores how digital imaging and three-dimensional (3D) printing can improve complex dental surgeries. Using tools such as computed tomography scans and intraoral scans, dentists can create detailed 3D models of a patient's bone and soft tissues. Two popular 3D printing methods-fused-filament fabrication (FFF) and stereolithography (SLA)-were used to make these models, which help with surgical planning. The study includes three cases where 3D-printed models were used to prepare for difficult dental procedures. In the first case, the 3D model helped plan the best way to access a difficult area for sinus surgery. The second case used the model to identify the best sites for bone harvesting. The third case used the model to plan how to safely expose an impacted tooth. These helped both the dentist and the patient understand the procedure better. All surgeries were successful, demonstrating how FFF and SLA 3D printing enhance planning, making advanced dental surgeries safer and more efficient.