Abstract
Purpose: Galectins (Gal) are a family of carbohydrate binding proteins that serve as regulators of fundamental numerous biological processes events like proliferation, cell adhesion and inflammation. Recently, specific galectins including Gal-1, -3, and -8 were shown to be overexpressed in human osteoarthritic cartilage and to trigger a gene signature in chondrocytes in vitro that is associated with inflammatory processes and matrix degradation. To date, however, the role of galectins in cartilage breakdown has not been elucidated using in vivo models, limiting mechanistic insights into their precise function.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
