Abstract
Chirality plays fundamental functions in the activity of biological molecules and broad classes of chemical reactions, but its recognition and detection still remain a great challenge. Herein, inspired by the stereo-control characteristics of chiral amino acids adjacent to the active sites of natural enzymes, a photoelectrochemical (PEC) chiral sensor was constructed by encapsulating Au nanoparticles with the recognition unit l-Cysteine into mesoporous BiVO4 skeleton. The chiral sensor exhibits a high sensitivity and selectivity discrimination of 3,4-dihydroxyphenylalanine (DOPA) enantiomers. The possible mechanism of enantioselectivity was proposed with the guidance of DFT calculations, suggesting that the origin of chiral selectivity lies in the different hydrogen bonds forms between l-Cys and DOPA. This work provides a powerful strategy for constructing PEC chiral sensing device with excellent chiral recognition performance.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
