Abstract
Discovery of Oosporein as a New Inhibitor of Influenza Virus Cap-snatching Activity
Highlights
During our screening of microbial origins, we found that fungal strain BF-0073 produces an inhibitor of the cap-snatching activity of influenza virus
Our research group has focused on the discovery of new compounds from microbial sources due to their great chemical diversity and interesting biological activity [1-5]
Over 1,000 microbial samples were screened, and fungal strain BF-0073 was selected for producing an inhibitor of the cap-snatching activity of influenza virus
Summary
During our screening of microbial origins, we found that fungal strain BF-0073 produces an inhibitor of the cap-snatching activity of influenza virus. Compound (1) was isolated from the culture broth of fungal strain BF-0073 by solvent extraction and preparative HPLC. Compound 1 inhibited the cap-snatching activity of influenza virus A Keywords:
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