Abstract
Antimicrobial peptides have distinct properties in terms of distribution and partitioning in bacterial populations due to their electric charge, hydrophobic interactions, and their mass absorption in dead cells. This leads to unexpected dynamics in dense bacterial populations, specially in biofilms where the cells are aggregated into defensive structures exhibiting community-level organizations for self-protection and resource sharing. To date, we do not have a direct evidence of how the action of AMPs is affected by the physical constraints and physiological diversity in biofilms structures.
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